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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ABCC6
All Species:
8.18
Human Site:
S261
Identified Species:
16.36
UniProt:
O95255
Number Species:
11
Phosphosite Substitution
Charge Score:
0.09
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O95255
NP_001162.4
1503
164906
S261
K
E
W
M
R
N
R
S
A
A
R
R
H
N
K
Chimpanzee
Pan troglodytes
XP_001145351
1247
137800
I130
K
S
S
T
V
G
E
I
V
N
L
M
S
V
D
Rhesus Macaque
Macaca mulatta
XP_001109862
1347
147568
P230
V
W
R
G
Y
R
R
P
L
R
P
K
D
L
W
Dog
Lupus familis
XP_547113
1504
165780
S261
R
E
W
T
R
T
R
S
A
A
Q
Q
H
T
K
Cat
Felis silvestris
Mouse
Mus musculus
Q9R1S7
1498
164770
N267
R
E
W
R
R
S
C
N
G
L
P
G
H
K
G
Rat
Rattus norvegicus
O88269
1502
164977
S267
R
E
W
R
R
N
F
S
E
L
P
G
H
K
G
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001517193
1537
172363
T278
K
N
W
A
K
E
C
T
K
S
K
K
Q
S
L
Chicken
Gallus gallus
Q5F364
1525
170953
A266
K
N
W
A
K
E
W
A
K
T
K
R
Q
P
L
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
XP_001341895
1518
169232
V266
R
R
W
D
Q
E
C
V
K
V
K
R
P
V
D
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P91660
1290
143990
G173
K
A
L
R
L
T
K
G
A
L
G
D
T
T
S
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9LZJ5
1539
172119
L262
F
I
S
K
T
F
W
L
W
M
N
P
L
L
R
Baker's Yeast
Sacchar. cerevisiae
P39109
1515
171103
E260
E
E
L
S
Q
K
L
E
K
N
W
E
N
E
L
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
39.6
84.9
79.5
N.A.
78.5
78.4
N.A.
45
45.3
N.A.
45.9
N.A.
28.2
N.A.
N.A.
N.A.
Protein Similarity:
100
55.6
86.8
87.3
N.A.
85.8
86
N.A.
63.5
63.2
N.A.
64.1
N.A.
46.9
N.A.
N.A.
N.A.
P-Site Identity:
100
6.6
6.6
60
N.A.
26.6
40
N.A.
13.3
20
N.A.
13.3
N.A.
13.3
N.A.
N.A.
N.A.
P-Site Similarity:
100
6.6
13.3
80
N.A.
46.6
46.6
N.A.
53.3
40
N.A.
33.3
N.A.
20
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
30.9
33.8
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
49.5
52.4
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
0
6.6
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
6.6
26.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
9
0
17
0
0
0
9
25
17
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
25
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
9
0
0
0
0
0
0
0
9
9
0
17
% D
% Glu:
9
42
0
0
0
25
9
9
9
0
0
9
0
9
0
% E
% Phe:
9
0
0
0
0
9
9
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
9
0
9
0
9
9
0
9
17
0
0
17
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
34
0
0
% H
% Ile:
0
9
0
0
0
0
0
9
0
0
0
0
0
0
0
% I
% Lys:
42
0
0
9
17
9
9
0
34
0
25
17
0
17
17
% K
% Leu:
0
0
17
0
9
0
9
9
9
25
9
0
9
17
25
% L
% Met:
0
0
0
9
0
0
0
0
0
9
0
9
0
0
0
% M
% Asn:
0
17
0
0
0
17
0
9
0
17
9
0
9
9
0
% N
% Pro:
0
0
0
0
0
0
0
9
0
0
25
9
9
9
0
% P
% Gln:
0
0
0
0
17
0
0
0
0
0
9
9
17
0
0
% Q
% Arg:
34
9
9
25
34
9
25
0
0
9
9
25
0
0
9
% R
% Ser:
0
9
17
9
0
9
0
25
0
9
0
0
9
9
9
% S
% Thr:
0
0
0
17
9
17
0
9
0
9
0
0
9
17
0
% T
% Val:
9
0
0
0
9
0
0
9
9
9
0
0
0
17
0
% V
% Trp:
0
9
59
0
0
0
17
0
9
0
9
0
0
0
9
% W
% Tyr:
0
0
0
0
9
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _